‘The losses of Alonso and Byrd mean two of the defense’s top playmakers — and maybe the top two — are gone. Dareus could be looking at an NFL suspension after his involvement in an offseason traffic accident, and the Bills don’t want to play too long without him. Spiller was probably as good last year as he’s been at any time in his pro career, but he still only scored two rushing touchdowns and his career high is six. The best thing for a young quarterback like Manuel might be a running game and a defense that sets the offense up in winning situations, but the Bills have to prove they have the pieces to make that formula work.’