‘RBs Fred Jackson and C.J. Spiller: The Bills lead the AFC in rushing due to both backs. Jackson has 462 yards from scrimmage (309 rushing, 153 receiving), which is fourth in the AFC, and scored two touchdowns against the Browns. His 28 first downs are tied for third in the league. Spiller is sixth in the AFC in rushing and averaged a league-best 6.0 yards per carry last year.’